Case Study

Overview

The client developed a novel bandage demonstrating high efficacy in treating skin tumors in animal studies.

Challenge

The project required a high loading of ceramic nanoparticles be incorporated directly into the nanofibers at the time of electrospinning. The manufacturing process needed to be translated from lab prototype scale to a continuous, commercial-ready scale.

Solution

Materic developed multiple solutions:

• A new, large-batch synthesis of the ceramic nanoparticle material
• A needleless electrospinning process capable of incorporating up to 50 wt% nanoparticles into the nanofiber
• A novel packaging system to eliminate nanoparticle loss during subsequent processing and application of the bandage

Outcome

• A bandage with equivalent efficacy to lab prototypes
• A scalable manufacturing process
• Process and performance data sufficient for FDA 510(k) filing

Early phase medical device company developing a therapeutic bandage

Additive Manufacturing, Analytical & Physical Testing, Biotechnology, Nanomaterials